A young boy recoils in pain as he is bitten by a lizard, which clings tenaciously to his finger. In the foreground is a magnificent still life of fruit, with a rose and sprig of jasmine in a glass vase. Look closely and you can see the reflection of a room in the curved surface of the vase. The painting may have an allegorical meaning and possibly refers to the pain that can derive from love.

This picture is the earliest of our three paintings by Michelangelo Merisi da Caravaggio and was probably painted in Rome in the mid-1590s, when the artist was beginning to find fame with his compelling and innovative style. It is very unusual for a late 16th-century painting to show such a moment of action, but Caravaggio rejected artistic convention and painted directly onto the canvas from live models. This gave his works an immediacy and intensity that made them instantly popular. Numerous early 17th-century copies and derivations of this painting exist, including a high-quality replica in the Fondazione Longhi, Florence, considered by many to be by Caravaggio himself.

Join us for a brief introduction to this painting, our picture of the month for June

Supported by Elizabeth and Daniel Peltz OBE