Detail from Ortolano, 'Saints Sebastian, Roch and Demetrius', about 1520
Saint Roch is believed to have special protective powers against the plague.
Born in Montpellier in 1295, he travelled to Italy to help cure plague victims. He became infected himself but was miraculously cured by an angel.
Explore more images of Saint Roch in the collection
The National Gallery, Trafalgar Square, London WC2N 5DN