Antonello's 'Portrait of a Man' is probably a relatively late work. It is likely that there was originally a parapet at the base bearing the painter's signature, but this has been removed.
Antonello was one of the first of the Italian artists to learn from Netherlandish art. The attention to detail and intensity of expression in the 'Portrait of a Man' are comparable to Netherlandish portraits. It is Antonello's mastery of oil paint which enables him to achieve these effects.