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The dead Christ is shown supported by the Virgin; on the right are Mary Magdalen and a Holy Woman; on the left are Saints John, Nicodemus and Joseph of Arimathaea.

The inscription has been translated as 'Andrea Busati, disciple of Giovanni Bellini, made this', but the reading of the second line is not certain.

This was formerly considered to be the earliest known work by Sebastiano del Piombo. The figure group is derived from a 'Lamentation by Cima' (Moscow, Pushkin Museum) which has been dated to about 1512.

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